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The 12mg dose produced the greatest average weight loss in the trial, but it was also associated with higher rates of gastrointestinal side effects

PubMed CrossRef Forslund M, Wndell P, Forsberg L, et al

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But for readers with fatty liver disease alongside MCAS or other inflammatory conditions, this is now one of the more evidence-supported areas for this class of medications and may be worth a conversation with your physician

4045 Linagliptin is the only DPP4 inhibitor excreted primarily via non-renal, and no dose adjustment is necessary in patients with CKD